A masterpiece of Isabeline Gothic, the chapel is by Enrique Egas. Inside, the spectacular grille by Bartolomé of Jaén closes off the transept, where the mausoleums of the Catholic Monarchs and their daughter Juana the Mad and her husband are housed. Note also the magnificent Plateresque retable of the high altar. The museum has objects of exceptional historical worth and an extraordinary collection of works by Spanish, Flemish and Italian masters.